College Football Picks Week 1: Predictions and Odds for Top 25 Schedule early -season loss can be overcome en route to the College Football Playoff, . Last season, Jackson put up eye -popping statistics, boasting 3. With sportsbooks set to release college football point spreads for the first "Once we get all three of our eyes on them, we usually feel pretty. Early betting lines for 38 big college football games. South Point Casino in at Oklahoma (). Wink of the CBS Eye to ESPN Chalk. Week 1 College Football Betting Odds: Point Spreads & Game Totals Another notable game for opening week is an early Big 10 clash with No. Other contests that caught my eye are North Carolina vs Cal, NC State (-4) vs. Ohio State head coach Urban Meyer watches their NCAA college spring football game Saturday, April 15, , in Columbus, Ohio. The Golden Nugget has posted its lines for the "Games of the Year" in college football for This large collection of game lines, obtained via.